Author

J. Lorent

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

O. Larsson· 2 shared A. D. Rao· 1 shared A. Descoteaux· 1 shared A. S. Trigos· 1 shared A. Zimmermann· 1 shared C. A. Martin· 1 shared C. Cullinane· 1 shared D. Goode· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

O. Larsson

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Author profile →

2 papers

Recent·Most cited

Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts

V. Chaparro, L.-P. Leroux, L. Masvidal, J. Lorent, T. E. Graber, A. Zimmermann, G. Arango Duque, A. Descoteaux, T. Alain, O. Larsson, M. Jaramillo

This study identifies mTOR- and eIF4A-sensitive immune-related transcripts in Leishmania donovani-infected macrophages, showing their role in modulating mRNA metabolism and immune responses.

bioRxiv · Dec 20, 2019Immunology

RNA binding kinase UHMK1 regulates therapy induced metabolic adaptation in BRAFV600 melanoma

L. K. Smith, T. Parmenter, M. Kleinschmidt, E. P. Kusnadi, J. Kang, C. A. Martin, P. Lau, J. Lorent, A. S. Trigos, T. Ward, A. D. Rao, E. J. Lelliott, K. E. Sheppard, D. Goode, R. J. Hicks, , G. A. McArthur

The paper identifies UHMK1 as a regulator of metabolic adaptation in BRAFV600 melanoma under targeted therapy, showing its role in mRNA transport and translation and its impact on therapy resistance.

bioRxiv · Sep 21, 2019Cancer Biology