Kynurenic acid promotes A1 to A2 astrocyte conversion against HIV-associated neurocognitive disorder
J. Lun, Y. Li, X. Gao, Z. Gong, X. Chen, J. Zou, C. Zhou, Y. Huang, B. Zhou, P. Huang, H. Cao
This study shows that kynurenic acid reduces A1 astrocyte activation and promotes A2 astrocyte formation, improving cognitive deficits in HIV-1 gp120 transgenic mice.
bioRxiv · Jul 11, 2022 · PreprintMicrobiology