Author

J. M. Antonucci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

K. Knecht· 2 shared L. Wu· 2 shared O. Buzovetsky· 2 shared Y. Xiong· 2 shared A. A. Duchon· 1 shared C. St. Gelais· 1 shared C. Tang· 1 shared K. M. Musier-Forsyth· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

K. Knecht

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2 papers

Recent·Most cited

MicrobiologybioRxivFeb 23, 2018

SAMHD1 Impairs HIV-1 Gene Expression and Reactivation of Viral Latency in CD4+ T-cells

J. M. Antonucci, S. H. Kim, C. St. Gelais…·L. Wu

This study shows that SAMHD1 suppresses HIV-1 gene expression and reactivation in CD4+ T-cells by binding to the HIV-1 LTR and inhibiting transcription.

DOI 10.1128/jvi.00292-18

humanbulk RNA-seq

𝕏 PostBluesky

BiophysicsbioRxivOct 24, 2017

The SAM domain of mouse SAMHD1 is critical for its activation and regulation

O. Buzovetsky, C. Tang, K. Knecht…·Y. Xiong

This study determines the first crystal structure of full-length mouse SAMHD1 in three nucleotide-bound states, revealing a more complex activation process involving the SAM domain compared to human SAMHD1.

DOI 10.1038/s41467-017-02783-8

mouseexperimental assay

𝕏 PostBluesky