Author

J. Mackenzie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 7 Approach:experimental assay· 6 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

D. R. de Zwaan· 2 shared S. Fritzlar· 2 shared S. Wang· 2 shared A. G. Brooks· 1 shared A. J. C. Steyn· 1 shared A. J. Olive· 1 shared C. M. Sassetti· 1 shared C. P. Simmons· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersEvolutionary Biology

D. R. de Zwaan

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Influenza infected macrophages release viral ribonucleoproteins that shape the local host response

S. Fritzlar, S. Lakdawala, J. A. Roberts, L. J. M. Coin, Y.-M. Deng, J. Moselen, V. Le Sage, J. Mackenzie, L. Labzin, A. G. Brooks, P. Reading, S. Londrigan

This study shows that influenza-infected macrophages release viral ribonucleoproteins (vRNPs) that trigger inflammatory responses in uninfected cells through the RIG-I/MDA5 pathway.

bioRxiv · Dec 4, 2023 · PreprintMicrobiology

Antiviral Wolbachia strains associate with Aedes aegypti endoplasmic reticulum membranes and disturb host cell lipid distribution to restrict dengue virus replication.

R. Kriiger-Loterio, E. Monson, R. Templin, J. T. Bruyne, H. A. Flores, J. Mackenzie, G. Ramm, K. Helbig, C. P. Simmons, J. E. Fraser

bioRxiv · Sep 14, 2023 · PreprintMicrobiology

Opposing dominance within a color gene block is associated with maladaptive hybrid signal discordance

D. R. de Zwaan, J. Mackenzie, E. Mikklesen, C. Wood, S. Wang

The study examines how opposing genetic dominance in a color gene block affects plumage signals and territorial behavior in hybrid songbirds, linking genetic variation to fitness outcomes.

bioRxiv · Feb 18, 2021 · PreprintEvolutionary Biology

Liquid chalk is an antiseptic against SARS-CoV-2 and influenza A respiratory viruses

J. L. McAuley, J. M. Deerain, W. Hammersla, T. E. Aktepe, D. J. F. Purcell, J. Mackenzie

The paper tests liquid chalk's antiseptic properties against SARS-CoV-2 and influenza A, finding it reduces infectious virus recovery in gym-like conditions.

bioRxiv · Nov 2, 2020Microbiology

Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase

Y. Cai, E. Jaecklein, J. Mackenzie, K. Papavinasasundaram, A. J. Olive, X. Chen, A. J. C. Steyn, C. M. Sassetti

This study shows that Mycobacterium tuberculosis relies on cytochrome bd oxidase to resist the adaptive immune response, particularly under acidic conditions in macrophages.

bioRxiv · Aug 21, 2020Microbiology

Selection on a pleiotropic color gene block underpins early differentiation between two warbler species

S. Wang, S. Rohwer, D. R. de Zwaan, D. P. L. Toews, I. J. Lovette, J. Mackenzie, D. E. Irwin

The paper identifies a pleiotropic gene block associated with plumage coloration that drives early differentiation between two hybridizing warbler species.

bioRxiv · Nov 25, 2019 · PreprintEvolutionary Biology

Mouse Norovirus infection arrests host cell translation uncoupled from the stress granule-PKR-eIF2α axis

S. Fritzlar, T. Aktepe, Y.-W. Chao, M. McAllaster, C. Wilen, P. White, J. Mackenzie

This study shows that mouse norovirus infection suppresses host translation and cytokine production while promoting viral replication by recruiting G3BP1 to block stress granule formation.

bioRxiv · Jan 31, 2019Microbiology