Author

J. McKerrow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

D. Skinner· 2 shared A. Aggarwal· 1 shared A. Ashhurst· 1 shared A. Drelich· 1 shared A. J. O'Donoghue· 1 shared A. O'Donoghue· 1 shared A. Parab· 1 shared A. Stoye· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. Skinner

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Discovery of Potent Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L

I. Meewan, J. Kattoula, J. Kattoula, D. Skinner, P. Fajtov, M. Giardini, B. Woodworth, J. McKerrow, J. Siqueira-Neto, A. J. O'Donoghue, R. Abagyan

This paper identifies potent triple inhibitors targeting SARS-CoV-2 proteases and human cathepsin L, showing improved potency and antiviral effects compared to disulfiram.

bioRxiv · Oct 19, 2021Pharmacology & Toxicology

Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L

A. Ashhurst, A. Tang, P. Fajtova, M. Yoon, A. Aggarwal, A. Stoye, M. Larance, L. Beretta, A. Drelich, D. Skinner, L. Li, T. Meek, J. McKerrow, V. Hook, C.-T. Tseng, , R. J. Payne

bioRxiv · Dec 23, 2020 · PreprintBiochemistry

Metabolite profiling of experimental cutaneous leishmaniasis lesions demonstrates significant perturbations in tissue phospholipids

L.-I. McCall, A. Parab, J. McKerrow, P. C. Dorrestein, D. Thomas, S. Lostracco-Johnson, J. L. de Siquiera-Neto

This study uses metabolomics to show significant changes in phospholipids in cutaneous leishmaniasis lesions and adjacent healthy tissue in mice.

bioRxiv · May 13, 2020Biochemistry