Author

J. Prigann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

C. Goffinet· 2 shared D. Postmus· 2 shared E. Wyler· 2 shared M. Landthaler· 2 shared A. J. Pietrobon· 1 shared A. Thiel· 1 shared A.-E. Saliba· 1 shared B. Gunsenheimer-Bartmeyer· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

C. Goffinet

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Neural Network-Assisted Humanization of COVID-19 Hamster scRNAseq Data Reveals Matching Severity States in Human Disease

V. D. Friedrich, P. Pennitz, E. Wyler, J. M. Adler, D. Postmus, L. G. T. Alves, J. Prigann, F. Pott, D. Vladimirova, T. Hoefler, C. Goekeri, M. Landthaler, C. Goffinet, A.-E. Saliba, M. Scholz, , G. Nouailles

This paper uses neural networks to match disease states between human and hamster COVID-19 scRNAseq data, finding similar cellular responses in specific cell types across species.

bioRxiv · Jan 11, 2024 · PreprintImmunology

Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunity

J. Prigann, D. Postmus, A. J. Pietrobon, E. Wyler, J. Jansen, L. Moeller, J. Fadejeva, T. Steijaert, C. Fischer, U. Koppe, B. Gunsenheimer-Bartmeyer, K. Meixenberger, S. Vitcetz, M. Sohn, L. Loyal, , C. GOFFINET

This study shows that type I interferons can enhance NK cell killing of HIV-1-reactivating T-cells despite HDACi-induced immune dysregulation, suggesting a potential strategy to improve shock-and-kill approaches.

bioRxiv · May 4, 2020 · PreprintMicrobiology