Author

M. Sohn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. Fischer· 2 shared C. Goffinet· 2 shared D. Postmus· 2 shared J. Jansen· 2 shared S. Sauer· 2 shared A. Grier· 1 shared A. J. Pietrobon· 1 shared A. Richter· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

C. Fischer

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Non-productive exposure of PBMCs to SARS-CoV-2 induces cell-intrinsic innate immunity responses

J. Kazmierski, K. Friedmann, D. Postmus, C. Fischer, J. Jansen, A. Richter, L. Bosquillon de Jarcy, C. Schüler, M. Sohn, S. Sauer, C. Drosten, A.-E. Saliba, L. Sander, D. Niemeyer, C. Goffinet

The paper shows that non-productive exposure of PBMCs to SARS-CoV-2 triggers JAK/STAT-dependent innate immune responses in monocytes, similar to those seen in mild COVID-19.

bioRxiv · Feb 15, 2022 · PreprintImmunology

Transkingdom Analysis of the Female Reproductive Tract Reveals Bacteriophages Form Communities

F. S. Madere, M. Sohn, A. Winbush, B. Barr, A. Grier, J. Java, T. Meiring, A.-L. Williamson, L.-G. Bekker, D. H. Adler, C. L. Monaco

The paper analyzes the FRT virome and bacteriome in BV-positive and BV-negative women, finding distinct bacteriophage signatures associated with bacterial vaginosis.

bioRxiv · Oct 12, 2021Microbiology

Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunity

J. Prigann, D. Postmus, A. J. Pietrobon, E. Wyler, J. Jansen, L. Moeller, J. Fadejeva, T. Steijaert, C. Fischer, U. Koppe, B. Gunsenheimer-Bartmeyer, K. Meixenberger, S. Vitcetz, M. Sohn, L. Loyal, , C. GOFFINET

This study shows that type I interferons can enhance NK cell killing of HIV-1-reactivating T-cells despite HDACi-induced immune dysregulation, suggesting a potential strategy to improve shock-and-kill approaches.

bioRxiv · May 4, 2020 · PreprintMicrobiology

Combined use of design of experiments and metabolic engineering for optimization of nogalamycin production

K. Maki, M. Coe, K. Brown, J. Tran, M. Sohn, E. Nybo

This study uses metabolic engineering and design of experiments to enhance nogalamycin production in Streptomyces nogalater, achieving a fourfold increase in yield through gene overexpression.

bioRxiv · Oct 13, 2019 · PreprintMicrobiology