Author

A. Thiel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. A. Kuehl· 1 shared A. C. Evans· 1 shared A. Huck· 1 shared A. J. Pietrobon· 1 shared B. Gunsenheimer-Bartmeyer· 1 shared B. Obermayer· 1 shared B. Siegmund· 1 shared C. Fischer· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperImmunology

A. A. Kuehl

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

3D reconstruction of ultra-high resolution neurotransmitter receptor atlases in human and non-human primate brains

T. Funck, K. Wagstyl, C. Lepage, M. Omidyeganeh, P. J. Toussaint, K. Amunts, A. Thiel, N. Palomero-Gallagher, A. C. Evans

The paper develops a method to reconstruct 3D neurotransmitter receptor maps from 2D histological sections, achieving high accuracy and creating atlases for human and macaque brains.

bioRxiv · Nov 18, 2022 · PreprintNeuroscience

HDAC7 controls anti-viral and anti-tumor immunity by CD8+ T cells

C. Yerinde, J. Keye, S. Durlanik, I. Freise, F. Nowak, H.-J. Hsiao, M. Letizia, S. Schlickeiser, B. Obermayer, A. Huck, M. Friedrich, H. Wu, D. Kunkel, A. A. Kuehl, S. Bauer, , C. Weidinger

This study shows HDAC7 regulates CD8+ T cell function by controlling survival, calcium homeostasis, and memory responses, impacting anti-viral and anti-tumor immunity in mice.

bioRxiv · Sep 18, 2022Immunology

Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunity

J. Prigann, D. Postmus, A. J. Pietrobon, E. Wyler, J. Jansen, L. Moeller, J. Fadejeva, T. Steijaert, C. Fischer, U. Koppe, B. Gunsenheimer-Bartmeyer, K. Meixenberger, S. Vitcetz, M. Sohn, L. Loyal, , C. GOFFINET

This study shows that type I interferons can enhance NK cell killing of HIV-1-reactivating T-cells despite HDACi-induced immune dysregulation, suggesting a potential strategy to improve shock-and-kill approaches.

bioRxiv · May 4, 2020 · PreprintMicrobiology