Cancer BiologybioRxiv
Tumor pre-conditioning of draining lymph node stroma by lactic acid
A. Riedel, J. Swietlik, D. Shorthouse…·J. Shields
This study identifies lactate as a tumor-derived metabolite that reprograms fibroblastic reticular cells in draining lymph nodes, altering their function and similarity to tumor-associated fibroblasts.
DOI 10.1158/2326-6066.cir-21-0778