Author

J.-P. Demers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:virus· 2

Frequent Co-Authors

D. Mannar· 2 shared K. Tuttle· 2 shared S. S. Srivastava· 2 shared S. Subramaniam· 2 shared S. Zhou· 2 shared W. Li· 2 shared X. Zhu· 2 shared A. Berezuk· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersBiochemistry

D. Mannar

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedFeb 8, 2022

Structural and Biochemical Rationale for Enhanced Spike Protein Fitness in Delta and Kappa SARS-CoV-2 Variants

J. W. Saville, D. Mannar, X. Zhu…·S. Subramaniam

This study examines structural and biochemical features of Delta and Kappa SARS-CoV-2 variants, showing increased ACE2 binding and antibody escape, contributing to Delta's dominance.

DOI 10.1038/s41467-022-28324-6

viruscryo-EM

𝕏 PostBluesky

BiophysicsbioRxivPreprintJan 11, 2021

Cryo-EM Structures of the N501Y SARS-CoV-2 Spike Protein in Complex with ACE2 and Two Potent Neutralizing Antibodies

X. Zhu, D. Mannar, S. S. Srivastava…·S. Subramaniam

The paper presents cryo-EM structures of the N501Y SARS-CoV-2 spike protein complex with ACE2 and neutralizing antibodies, showing increased ACE2 binding affinity and retained epitopes.

DOI 10.1101/2021.01.11.426269

viruscryo-EM

𝕏 PostBluesky