Author

K. Arai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Y. Tanaka· 2 shared C. Kent· 1 shared F. Ma· 1 shared G. W.-Y. Cheng· 1 shared H. Hojo· 1 shared H. Kasahara· 1 shared H. Yamaguchi· 1 shared H.-S. Yi· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

Y. Tanaka

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

White matter hyperintensity genetic risk factor TRIM47 regulates autophagy in brain endothelial cells

S. H.-S. Yeung, R. H.-S. Lee, G. W.-Y. Cheng, I. W.-T. Ma, J. Kofler, C. Kent, F. Ma, K. Herrup, M. Fornage, K. Arai, K.-H. Tse

The paper identifies TRIM47 as a genetic risk factor for white matter hyperintensity and shows it inhibits autophagy in brain endothelial cells.

bioRxiv · Dec 18, 2023Cell Biology

Dose-response relationship for the resistance of human insulin to degradation by insulin-degrading enzyme

M. Okumura, T. Kuramochi, Y. Lin, R. Furukawa, K. Mizutani, T. Yokoyama, M. Kim, M. H. Lim, H.-S. Yi, K. Arai, H. Yamaguchi, H. Hojo, M. Iwaoka, Y. Tanaka, S.-Y. Park, , Y.-H. Lee

The paper investigates how human insulin resistance to degradation by IDE varies with dose and identifies structural features of the insulin hexamer that influence degradation kinetics without zinc.

bioRxiv · Apr 8, 2023 · PreprintBiochemistry

Chemical inhibition of auxin inactivation pathway uncovers the metabolic turnover of auxin homeostasis

K. Fukui, K. Arai, Y. Tanaka, Y. Aoi, V. Kukshal, J. M. Jez, M. F. Kubes, R. Napier, Y. Zhao, H. Kasahara, K.-i. Hayashi

This study inhibits the auxin inactivation pathway using a novel chemical inhibitor, revealing rapid auxin turnover and dynamic regulation of auxin homeostasis.

bioRxiv · Oct 12, 2021 · PreprintPlant Biology

Temporal analysis of localization and trafficking of glycolipids

K. Arai, K. Kabayama, Y. Kanie, O. Kanie, K. Fukase

The paper tracks glycolipid trafficking using fluorescent probes and identifies a recycling pathway through the trans-Golgi network without lysosomal involvement.

bioRxiv · Apr 7, 2020Biochemistry