K. Balabanian

This paper develops a 3D artificial marrow organoid model to study NK and myeloid cell differentiation, showing improved immune receptor expression and drug response compared to 2D models.

This study shows that CXCR4 signaling strength influences hematopoietic multipotent progenitor fate through both extrinsic and intrinsic mechanisms, with implications for myeloid skewing in WHIM Syndrome.

This study identifies Sec22b as a critical regulator of plasma cell maintenance and function by controlling organelle dynamics, leading to reduced antibody secretion and impaired immune response.

This study shows that CXCR4 desensitization is crucial for regulating B cell activation, plasma cell differentiation, and migration in the extra-follicular response.