Author

K. Clement

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

G. Marcelin· 2 shared L. Yvan-Charvet· 2 shared M. Ouhachi· 2 shared S. Dussaud· 2 shared T. Huby· 2 shared A. Ferreira· 1 shared A. Gelineau· 1 shared A. Gnirke· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPathology

G. Marcelin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Obesity-elicited macrophages shape CD9hi progenitor fate to promote adipose tissue fibrosis and dysfunction

H. Askia, S. Dussaud, M. Chaves de Oliveira, A. Oliveira, L. Poupel, C. Rebiere, M. Ouhachi, R. Manuel, F. Merabtene, L. Genser, J. Aron-Wisnewsky, M. Moreau, L. Yvan-Charvet, A. Ferreira, T. Huby, , E. Gautier

This study identifies an interaction between obesity-elicited macrophages and CD9hi progenitors that drives adipose tissue fibrosis and dysfunction in mice and humans.

bioRxiv · Sep 26, 2023 · PreprintPathology

Novel mechanism of MYC deregulation in Multiple Myeloma

M. Rahmat, K. Clement, J.-B. Alberge, R. Sklavenitis-Pistofidis, R. Kodgule, C. Fulco, D. Heilpern-Mallory, K. Nilsson, D. Dorfman, J. Engreitz, G. Getz, L. Pinello, R. Ryan, I. M. Ghobrial

The paper identifies a new epigenetic mechanism of MYC deregulation in multiple myeloma through enhancer accessibility and transcription factor binding, independent of translocations or amplifications.

bioRxiv · May 19, 2023 · PreprintCancer Biology

Dietary fibers benefits on glucose homeostasis require type 2 conventional dendritic cells in mice fed a high-fat diet

A. Gelineau, G. Marcelin, M. Ouhachi, S. Dussaud, L. Voland, I. Baba, C. Rouault, L. Yvan-Charvet, K. Clement, R. Tussiwand, T. Huby, E. L. Gautier

This study shows that dietary fibers improve glucose tolerance in mice on a high-fat diet by maintaining specific immune cells, and this effect depends on type 2 conventional dendritic cells.

bioRxiv · Apr 19, 2023Immunology

Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to graft-versus-leukemia

P. Bachireddy, C. Ennis, V. Nguyen, K. Clement, S. H. Gohil, S. A. Shukla, J. Forman, N. Barkas, S. Freeman, N. Bavli, L. Elagina, I. Leshchiner, A. W. Mohammad, L. Z. Rassenti, T. J. Kipps, , C. J. Wu

The paper investigates the evolutionary trajectories of chronic lymphocytic leukemia cells during resistance to graft-versus-leukemia, finding distinct genetic and epigenetic dynamics post-transplant compared to chemotherapy.

bioRxiv · Apr 9, 2020Cancer Biology

Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease

O. Govaere, S. K. Petersen, N. Martinez-Lopez, J. Wouters, M. Van Haele, R. M. Mancina, O. Jamialahmadi, O. Bilkei-Gorzo, P. B. Lassen, R. Darlay, J. Peltier, J. M. Palmer, R. Younes, D. Tiniakos, G. P. Aithal, , A. Hartlova

This study identifies MSR1 as a key mediator of lipid-induced inflammation in NAFLD, showing its role in macrophage activation and potential as a therapeutic target.

bioRxiv · Feb 1, 2020Immunology