Author

K. Howe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cancer Biology· 1 Immunology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:whole-genome sequencing· 4 Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2

Frequent Co-Authors

W. Chow· 3 shared J. Wood· 2 shared S. McCarthy· 2 shared A. Baez-Ortega· 1 shared A. Bendesky· 1 shared A. Bours· 1 shared A. Girgis· 1 shared A. Hayward· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersEvolutionary Biology

W. Chow

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The sensory shark: high-quality morphological, genomic and transcriptomic data for the small spotted catshark Scyliorhinus canicula reveal the molecular bases of sensory organ evolution in jawed vertebrates

H. Mayeur, J. Leyhr, J. Mulley, L. Nicolas, L. Michel, K. Sharma, R. Lagadec, J.-M. Aury, O. G. Osborne, P. Mulhair, J. Poulain, S. Mangenot, D. Mead, M. Smith, C. Corton, , M. Debiais-Thibaud

This study integrates genomic, transcriptomic, and morphological data from the small-spotted catshark to uncover molecular mechanisms underlying sensory organ evolution in jawed vertebrates.

bioRxiv · May 23, 2024 · PreprintEvolutionary Biology

Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade

D. H. Shu, W. J. Ho, L. T. Kagohara, A. Girgis, S. M. Shin, L. Danilova, J. W. Lee, D. N. Sidiropoulos, S. Mitchell, K. Munjal, K. Howe, K. J. Bendinelli, H. Qi, G. Mo, J. Montagne, , M. Yarchoan

This study examines TLS in HCC treated with neoadjuvant immunotherapy, finding TLS correlate with better outcomes and show distinct morphological and functional features in tumor regression.

bioRxiv · Oct 16, 2023 · PreprintImmunology

The evolution of two transmissible cancers in Tasmanian devils

M. R. Stammnitz, K. Gori, Y. M. Kwon, E. Harry, F. J. Martin, K. Billis, Y. Cheng, A. Baez-Ortega, W. Chow, S. Comte, H. Eggertsson, S. Fox, R. Hamede, M. E. Jones, B. Lazenby, , E. P. Murchison

This study analyzes the genetic diversity and evolution of two transmissible cancers in Tasmanian devils, revealing their emergence dates, mutation rates, and evolutionary patterns.

bioRxiv · May 27, 2022Cancer Biology

Distinct patterns of genetic variation at low-recombining genomic regions represent haplotype structure

J. Ishigohoka, K. Bascon-Cardozo, A. Bours, J. Fuss, A. Rhie, J. Mountcastle, B. Haase, W. Chow, J. Collins, K. Howe, M. Uliano-Silva, O. Fedrigo, E. D. Jarvis, J. Perez-Tris, J. C. Illera, M. Liedvogel

The paper identifies distinct genetic variation patterns in low-recombining regions of Eurasian blackcap genomes, attributing them to reduced recombination rates rather than selection.

bioRxiv · Dec 22, 2021Evolutionary Biology

Genomic consequences of domestication of the Siamese fighting fish

Y. Kwon, N. Vranken, C. Hoge, M. R. Lichak, K. X. Francis, J. Camacho-Garcia, I. Bista, J. Wood, S. McCarthy, W. Chow, H. H. Tan, K. Howe, S. Bandara, J. von Lintig, L. Ruber, , A. Bendesky

The paper uses genomic data to show betta fish were domesticated over 1,000 years ago and identifies genes involved in their phenotypic diversity.

bioRxiv · Apr 29, 2021Evolutionary Biology

Water transmission potential of Angiostrongylus cantonensis: larval viability, and effectiveness of rainwater catchment sediment filters

K. Howe, L. Kaluna, B. T. Fisher, Y. Tagami, R. McHugh, S. I. Jarvi

This study investigates the viability of Angiostrongylus cantonensis larvae in water and their ability to pass through rainwater filters, highlighting risks for waterborne transmission of neuroangiostrongyliasis.

bioRxiv · Dec 13, 2018Zoology