A. Hayward

High-throughput investigation of genetic design constraints in domesticated Influenza A Virus for transient gene delivery

The paper investigates genetic design constraints in domesticated Influenza A Virus for transient gene delivery, identifying permissible mutations and RNA level motif depletion.

Electroadhesive hydrogel interface for prolonged mucosal theranostics

This paper develops e-GLUE, an electroadhesive hydrogel interface that enables prolonged mucosal retention and demonstrates its utility in GI theranostics.

Drinkable, liquid in situ-forming and tough hydrogels for gastrointestinal therapeutics

This paper develops LIFT hydrogels that form in the stomach to deliver drugs with controlled release, improving bioavailability and reducing toxicity.

Graphene-based thin film microelectrode technology for in vivo high resolution neural recording and stimulation

This paper introduces a graphene-based thin film microelectrode technology for high-resolution in vivo neural recording and stimulation, showing low impedance, high charge injection, and good biocompatibility.

Chromosome fissions and fusions act as barriers to gene flow between Brenthis fritillary butterflies

This study shows chromosome fissions and fusions reduce gene flow between sympatric Brenthis fritillary butterflies by lowering effective migration rates in rearranged genomic regions.

Absorbable Conductive Electrotherapeutic Scaffolds (ACES) for Enhanced Peripheral Nerve Regeneration and Stimulation

This paper introduces ACES, absorbable conductive scaffolds that enhance peripheral nerve regeneration and stimulation in animal models.

BREAKING THE TIGHT GENETIC LINKAGE BETWEEN THE a1 AND sh2 GENES LED TO THE DEVELOPMENT OF ANTHOCYANIN-RICH PURPLE-PERICARP SUPER-SWEETCORN

This paper reports the development of purple-pericarp super-sweetcorn by breaking the tight genetic linkage between a1 and sh2 genes, resulting in a plant with anthocyanin-rich purple pericarp and high sugar content.

The genome sequence of the scarce swallowtail, Iphiclides podalirius

This paper presents a chromosome-level genome assembly for the scarce swallowtail butterfly and reports a negative correlation between chromosome length and heterozygosity at fourfold-degenerate sites.

The genome sequence of the lesser marbled fritillary, Brenthis ino, and evidence for a segregating neo-Z chromosome

This paper presents a chromosome-level genome assembly for the lesser marbled fritillary, Brenthis ino, and provides evidence for a segregating neo-Z chromosome in males.

Bacterial colonisation dynamics of household plastics in a coastal environment

The paper tracks bacterial colonisation of household plastics in a coastal environment, finding rapid colonisation by diverse bacteria, including pathogens, regardless of polymer type.

Functionally distinct T-helper cell phenotypes predict resistance to different types of parasites in a wild mammal

The study shows that Th1 and Th2 immune responses predict resistance to different parasites in wild Soay sheep, supporting lab findings in natural settings.

The Pleistocene species pump past its prime: evidence from European butterfly sister species

The paper estimates divergence times for European butterfly sister species using genome-wide transcriptome data, finding most diverged before the Pleistocene and showing contact zones are not limited to early speciation stages.

The influence of liver fluke infection on production in sheep and cattle: a meta-analysis

This study conducts a meta-analysis to quantify the impact of liver fluke infection on livestock performance traits and identifies study design factors influencing results.

Tolerance of liver fluke infection varies between breeds and producers in Scottish beef cattle

This study shows that beef cattle vary in their tolerance to liver fluke infection, with differences observed between breeds and producers.

Horseshoe crab genomes reveal the evolutionary fates of genes and microRNAs after three rounds (3R) of whole genome duplication

Individualized System for Augmenting Ventilator Efficacy (iSAVE):A Rapidly deployable system to expand ventilator capacity

The paper introduces iSAVE, a system to safely use a single ventilator for multiple patients during ventilator shortages, demonstrating its effectiveness in simulated and pig trials.

Millipede genomes reveal unique adaptation of genes and microRNAs during myriapod evolution

This paper sequenced two millipede genomes, revealing unique genomic features, defense systems, and microRNA regulation mechanisms in myriapods.

The determinants of genetic diversity in butterflies - Lewontin's paradox revisited

This study examines genetic diversity in European butterflies and finds it correlates with body size and genetic map length, not population size or fecundity.