Author

K. Lange

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. A. Ricci· 1 shared A. B. Hill· 1 shared A. F. Thompson· 1 shared A. G. Johnson· 1 shared A. Leikin-Frenkel· 1 shared A. Millman· 1 shared A. Sacconi· 1 shared A. Schaffer· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. A. Ricci

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inactivation of p53 drives breast cancer brain metastasis by altering fatty acid metabolism

K. Laue, S. Pozzi, Y. Cohen-Sharir, T. Winkler, Y. Eliezer, S. Israeli Dangoor, A. Leikin-Frenkel, K. Lange, J. Zerbib, A. A. Ricci, A. Sacconi, J. Berthelet, A. Schaffer, W. Shi, Y. Liao, , U. Ben-David

This study shows that p53 inactivation promotes breast cancer brain metastasis by altering fatty acid metabolism, with implications for therapeutic targeting.

bioRxiv · Dec 20, 2023 · PreprintCancer Biology

CARD-like domains mediate anti-phage defense in bacterial gasdermin systems

T. Wein, A. G. Johnson, A. Millman, K. Lange, E. Yirmiya, R. Hadary, J. Garb, F. Steinruecke, A. B. Hill, P. J. Kranzusch, R. Sorek

This study identifies CARD-like domains in bacterial defense systems that activate gasdermin-mediated cell death against phage infection.

bioRxiv · May 28, 2023 · PreprintMicrobiology

Reconstitution of renal cyst formation in 3D culture reveals a role for AMOT and Yap1 in determining cyst size.

C. D. Wells, K. Lange, A. F. Thompson, W. M. Xu, S. G. Clendenon, J. S. Underwood, P. Harris, B.-S. Herbert, J. A. Glazier, A. Wandinger-Ness, R. L. Bacallao

The paper shows that Cadherin 8 and YAP1 drive cyst initiation and expansion, respectively, in 3D kidney cultures, with AMOTL1 inhibiting expansion.

bioRxiv · Mar 1, 2022 · PreprintCell Biology