K. M. Beussman

This study shows that perpendicular shear stress drives helical transmural remodeling in engineered human ventricles, revealing how physical forces influence cardiac architecture.

This paper introduces a traction force microscopy technique called 'black dots' to measure cellular forces without constraining cell shape, finding that higher force correlates with increased spread area, circularity, and F-actin uniformity in platelets.

This paper introduces a rainbow reporter system for tracking single cell dynamics in pluripotent stem cells and their derivatives, revealing heterogeneous behaviors during clonal expansion and differentiation.

The paper uses a fluorescent barcoding system to track clonal expansion of engrafted hPSC-CMs in vivo, finding that some cells proliferate while others hypertrophy without dividing.