ImmunologybioRxivPreprint
Cellular polarity asymmetrically functionalizes pathogen recognition receptor-mediated intrinsic immune response in human intestinal epithelium cells
M. Stanifer, S. Muenchau, K. Pervolaraki…·S. Boulant
The paper shows that AP-1B-mediated polarized sorting of TLR3 leads to an asymmetric immune response in human intestinal epithelial cells to basolateral vs. apical infections.