K. R. Jerome

This study demonstrates that a viral gene drive can spread in vivo during HSV-1 infection in mice by promoting co-infection and recombination.

The paper reanalyzes scRNA-Seq data and finds that HSV-1 latency in non-neuronal ganglionic cells is not supported, attributing the previous findings to technical artifacts.

This study tracks HRV evolution in immunocompromised patients, finding no genetic adaptation for URT to LRT progression and highlighting capsid variability and mutation-independent compartmentalization.

This study shows liver-humanized NSG-PiZ mice can support chronic HBV infection and antiviral therapy research, with prolonged viremia and responsiveness to entecavir.

This study investigates SARS-CoV-2 transmission on a fishing boat, finding low within-host viral diversity and limited viral evolution during the outbreak.

This study examines how SARS-CoV-2 induces antiviral host responses, showing differences by viral load, age, and sex in gene expression profiles from infected individuals.

This paper shows SARS-CoV-2 ORF6 interacts with Rae1 and Nup98 to disrupt nucleocytoplasmic transport, reducing reporter expression and causing nuclear mRNA accumulation, more strongly than SARS-CoV ORF6.

This paper tests a direct RT-qPCR method for detecting SARS-CoV-2 RNA in nasal swabs without RNA extraction, achieving 92% accuracy on blinded samples.

This study identifies copy number heterogeneity in JC virus standards using next-generation sequencing, revealing significant genomic coverage variation due to large deletions.