Author

K. Ramlaul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 4 Research Focus:protein structure prediction· 4 Approach:experimental assay· 3 Approach:deep learning· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

C. H. S. Aylett· 5 shared N. de Martin Garrido· 4 shared A. Burt· 1 shared A. Jakobi· 1 shared A. Litvinova· 1 shared A. S. Melnikov· 1 shared B. Li· 1 shared C. Canavan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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5 shared papersBiophysics

C. H. S. Aylett

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Author profile →

5 papers

Recent·Most cited

A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate

K. Ramlaul, Z. Feng, C. Canavan, N. de Martin Garrido, D. Carreno, M. Crone, K. E. Jensen, B. Li, H. Barnet, D. T. Riglar, P. S. Freemont, D. Miller, C. H. S. Aylett

This paper introduces a 3D-printed flow-cell device for on-grid affinity purification of cryo-EM samples directly from lysate, aiming to improve sample preparation efficiency.

bioRxiv · Mar 17, 2023Biophysics

Structure of the Bacteriophage PhiKZ non-Virion RNA Polymerase

N. de Martin Garrido, M. Orekhova, Y. T. E. Lai Wan Loong, A. Litvinova, K. Ramlaul, T. Artamonova, A. S. Melnikov, P. Serdobintsev, C. H. S. Aylett, M. Yakunina

The paper resolves the structure of the Bacteriophage PhiKZ non-virion RNA polymerase, revealing its assembly, homology, and the role of a fifth subunit.

bioRxiv · Apr 6, 2021Biochemistry

Direct information estimation from cryo-EM Movies with CARYON

K. Ramlaul, A. Burt, N. de Martin Garrido, J. MacDonald, C. Palmer, A. Jakobi, C. H. S. Aylett

This study measures information content in cryo-EM movies to improve parameter estimation for 3D reconstruction, introducing the CARYON filter for enhanced image processing.

bioRxiv · Nov 25, 2020 · PreprintBiophysics

Architecture of the Tuberous Sclerosis Protein Complex

K. Ramlaul, W. Fu, H. Li, N. de Martin Garrido, L. He, W. Cui, C. H. S. Aylett, G. Wu

This study uses cryo-EM to determine the structure of the TSCC complex, revealing its architecture and potential mechanisms of Rheb regulation.

bioRxiv · Sep 29, 2020Cell Biology

Mitigating Local Over-fitting During Single Particle Reconstruction with SIDESPLITTER

K. Ramlaul, C. M. Palmer, C. H. S. Aylett

This paper introduces SIDESPLITTER, a method to reduce over-fitting in single particle cryo-EM reconstruction by applying a local signal-to-noise filter during refinement.

bioRxiv · Dec 12, 2019Biophysics