Author

K. S. Kao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

J. V. Ravetch· 2 shared R. Yamin· 2 shared A. Gupta· 1 shared C. M. Rice· 1 shared D. A. Oren· 1 shared E. Sundberg· 1 shared J. Du· 1 shared M. R. MacDonald· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

J. V. Ravetch

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 23, 2023

Mechanism of glycoform specificity and protection against antibody dependent enhancement by an anti-afucosylated IgG nanobody

A. Gupta, K. S. Kao, R. Yamin…·J. V. Ravetch

This paper presents the X-ray structure of a nanobody that binds afucosylated IgG1 Fc and disrupts pathogenic interactions, rescuing mice in a dengue model.

DOI 10.1101/2023.01.23.525277

protein structureexperimental assay

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 2, 2022

Human FcγRIIIa activation on splenic macrophages drives the in vivo pathogenesis of dengue disease

R. Yamin, K. S. Kao, M. R. MacDonald…·S. Bournazos

This study shows that anti-DENV IgG antibodies drive dengue pathogenesis via FcγRIIIa on splenic macrophages, leading to inflammation and mortality.

DOI 10.1101/2022.11.02.514909

mouseexperimental assay

𝕏 PostBluesky