Mechanism of glycoform specificity and protection against antibody dependent enhancement by an anti-afucosylated IgG nanobody
A. Gupta, K. S. Kao, R. Yamin…·J. V. Ravetch
This paper presents the X-ray structure of a nanobody that binds afucosylated IgG1 Fc and disrupts pathogenic interactions, rescuing mice in a dengue model.