Author

K. Schmidt-Bleek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 5 Organism:mouse· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

G. N. Duda· 5 shared A. Cipitria· 3 shared C. A. Garrido· 3 shared C. H. Bucher· 2 shared D. S. Garske· 2 shared S. Amini· 2 shared A. Damerau· 1 shared A. E. Hauser· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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5 shared papersBioengineering

G. N. Duda

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Anisotropic Hydrogel Degradation Enhances 3D Collective Mesenchymal Stromal Cell Alignment, Mechanotransduction and Osteogenic Differentiation

C. A. Garrido, D. S. Garske, C. H. Bucher, S. Amini, G. N. Duda, K. Schmidt-Bleek, A. Cipitria

This paper shows that anisotropic hydrogel degradation patterns enhance hMSC alignment, mechanotransduction, and osteogenic differentiation compared to uniform materials.

bioRxiv · Apr 11, 2024Bioengineering

Aging impairs skeletal muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution via fibro-adipogenic progenitors

F. Garcia-Carrizo, S. Gohlke, G. Lenihan-Geels, A.-M. Jank, M. Leer, G. A. Soultoukis, M. Oveisi, C. Herpich, C. A. Garrido, G. Kotsaris, S. Poehle-Kronawitter, A. Tsamo-Tetou, A. Graja, M. Ost, L. Villacorta, , T. J. Schulz

This study shows aging impairs muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution through reduced Periostin in fibro/adipogenic progenitors.

bioRxiv · Nov 27, 2023 · PreprintPhysiology

Hydrogels with stiffness-degradation spatial patterns control anisotropic 3D cell response

C. A. Garrido, D. S. Garske, M. Thiele, S. Amini, S. Real, G. N. Duda, K. Schmidt-Bleek, A. Cipitria

This study develops hydrogels with spatial stiffness-degradation patterns to control anisotropic 3D cell response, showing changes in cell morphology and proliferation over time.

bioRxiv · Jan 25, 2023Bioengineering

In vivo validation of spray-dried mesoporous bioactive glass microspheres acting as prolonged local release systems for BMP-2 to induce bone regeneration

J. C. Berkmann, A. X. Herrera Martin, C. Pontremoli, K. Zheng, C. H. Bucher, A. Ellinghaus, A. R. Boccaccini, S. Fiorilli, C. Vitale-Brovarone, G. N. Duda, K. Schmidt-Bleek

This study validates spray-dried mesoporous bioactive glass microspheres as a prolonged BMP-2 release system to enhance bone regeneration with reduced side effects.

Pharmaceutics · Aug 28, 2020Peer-reviewedCell Biology

HIF-stabilization prevents delayed fracture healing

A. Lang, S. Helfmeier, J. Stefanowski, A. Kuppe, V. Sunkara, M. Pfeiffenberger, A. Wolter, A. Damerau, S. Hemmati-Sadeghi, J. Ringe, R. Haag, A. E. Hauser, M. Loehning, C. Perka, G. N. Duda, , F. Buttgereit

This study shows that stabilizing HIF-1α with deferoxamine and macrophage migration inhibitory factor improves fracture healing in a mouse model by enhancing calcification, osteogenic differentiation, and vascularization.

bioRxiv · Jul 2, 2020Bioengineering

Distinct housing conditions reveal a major impact of adaptive immunity on the course of obesity-induced type 2 diabetes

J. Sbierski-Kind, J. Kath, S. Brachs, M. Streitz, M. von Herrath, A. Kuehl, K. Schmidt-Bleek, K. Mai, J. Spranger, H.-D. Volk

This study shows that housing conditions affect adaptive immunity and metabolic outcomes in obesity-induced type 2 diabetes, with antigen-exposed mice showing improved glucose tolerance but liver inflammation.

bioRxiv · Mar 15, 2018Immunology