Author

K. Mai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 4 Assay:proteomics· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Organism:zebrafish· 2

Frequent Co-Authors

W. Xu· 2 shared W. Zhang· 2 shared A. Ablasser· 1 shared A. Kuehl· 1 shared A. M. C. Boehner· 1 shared A. Roesen-Wolff· 1 shared A. Sato· 1 shared B. Guo· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

W. Xu

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Tip60-mediated Rheb acetylation links palmitic acid with mTORC1 activation and insulin resistance

Z. Zhao, Q. Chen, X. Xiang, W. Dai, W. Fang, K. Cui, B. Li, Q. Liu, Y. Liu, Y. Shen, Y. Li, W. Xu, K. Mai, Q. Ai

This study shows that palmitic acid induces mTORC1 activation via Tip60-mediated Rheb acetylation, leading to insulin resistance, while unsaturated fatty acids do not.

bioRxiv · Aug 18, 2023Cell Biology

Synergistic effects of dietary taurine and carbohydrates supplementation on skeleton muscle of juvenile turbot Scophthalmus maximus

H. Hays, W. Zhang, K. Mai

This study examines how dietary taurine and carbohydrate levels affect skeletal muscle growth in juvenile turbot, finding that 1.2% taurine with 21% carbohydrates significantly enhances muscle fiber hyperplasia and collagen content.

bioRxiv · May 10, 2023 · PreprintCell Biology

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

N. Kessler, S. F. Viehmann, C. Krollmann, K. Mai, K. M. Kirschner, H. Luksch, P. Kotagiri, A. M. C. Boehner, D. Huugen, C. C. de Oliveira Mann, S. Otten, S. A. I. Weiss, T. Zillinger, K. Dobrikova, D. E. Jenne, , N. Garbi

This study identifies cGAS/STING/IFN-mediated nucleic acid sensing by monocyte-derived macrophages as a driver of severe pulmonary vasculitis and shows that targeting this pathway reduces disease severity.

bioRxiv · May 30, 2022Immunology

SARS-CoV-2 bearing a mutation at the S1/S2 cleavage site exhibits attenuated virulence and confers protective immunity

M. Sasaki, S. Toba, Y. Itakura, H. M. Herman M. Chambaro, K. Mai, K. Tabata, K. Intaruck, K. Uemura, T. Sanaki, A. Sato, W. W. Hall, Y. Orba, H. Sawa

This study shows that SARS-CoV-2 variants with mutations at the furin cleavage site are less virulent and induce protective immunity in hamsters.

bioRxiv · Apr 29, 2021Microbiology

Distinct housing conditions reveal a major impact of adaptive immunity on the course of obesity-induced type 2 diabetes

J. Sbierski-Kind, J. Kath, S. Brachs, M. Streitz, M. von Herrath, A. Kuehl, K. Schmidt-Bleek, K. Mai, J. Spranger, H.-D. Volk

This study shows that housing conditions affect adaptive immunity and metabolic outcomes in obesity-induced type 2 diabetes, with antigen-exposed mice showing improved glucose tolerance but liver inflammation.

bioRxiv · Mar 15, 2018Immunology

A negative feedback mechanism in the insulin-regulated glucose homeostasis in Japanese flounder Paralichthys olivaceus by two ways of glucose administration

D. Liu, D. Han, B. Guo, K. Deng, Z. Gu, M. Yang, W. Xu, W. Zhang, K. Mai

This study compares glucose administration methods in Japanese flounder, showing different insulin and brain-gut peptide responses, and suggests a negative feedback mechanism in glucose homeostasis.

bioRxiv · Aug 9, 2017Biochemistry