Author

K. Tsuchikama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

A. Yamaguchi· 2 shared N. Zhang· 2 shared W. Xiong· 2 shared Y. Anami· 2 shared Y. Otani· 2 shared Z. An· 2 shared B. Kaur· 1 shared C. M. Yamazaki· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBioengineering

A. Yamaguchi

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2 papers

Recent·Most cited

BioengineeringbioRxivDec 23, 2021

Homogeneity of antibody-drug conjugates critically impacts the therapeutic efficacy in brain tumors

Y. Anami, Y. Otani, W. Xiong…·K. Tsuchikama

This study shows that homogeneous antibody-drug conjugates (ADCs) improve therapeutic efficacy in glioblastoma models compared to heterogeneous ADCs.

DOI 10.1016/j.celrep.2022.110839

mouseexperimental assay

𝕏 PostBluesky

BioengineeringNature CommunicationsPeer-reviewedJun 10, 2021

Antibody-drug conjugates with dual payloads for combating breast tumor heterogeneity and drug resistance

C. M. Yamazaki, A. Yamaguchi, Y. Anami…·K. Tsuchikama

This study develops dual-payload antibody-drug conjugates to overcome breast tumor heterogeneity and drug resistance, showing improved efficacy in a xenograft model.

DOI 10.1038/s41467-021-23793-7

mouseexperimental assay

𝕏 PostBluesky