ImmunologybioRxiv
Centrioles control the capacity, but not the specificity, of cytotoxic T cell killing
F. Tamzalit, D. Tran, W. Jin…·M. Huse
This study shows that centrioles affect the capacity but not the specificity of cytotoxic T cell killing by impacting granule biogenesis and actin remodeling, not granule polarization.
DOI 10.1073/pnas.1913220117