Author

K. Weeks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Boppana· 1 shared A. El-Osta· 1 shared A. Gladfelter· 1 shared A. R. Pinto· 1 shared C. A. Roden· 1 shared C. D. Cohen· 1 shared C. Iserman· 1 shared C. Johnson· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. Boppana

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Immune-induced remodelling of mRNA structurome regulates uORF-mediated translation

Y. Xiang, T. Chen, P. S. Irving, K. Weeks, X. Dong

The paper identifies how immune stress remodels mRNA structures to regulate uORF-mediated translation in Arabidopsis by unwinding RNA structures via RNA helicases.

bioRxiv · May 9, 2023 · PreprintPlant Biology

Maternal diet and gut microbiota influence predisposition to cardiovascular disease in the offspring

H. A. Jama, M. I. Dona, E. Dinakis, M. Nakai, M. R. Paterson, W. Shihata, C. Krstevski, C. D. Cohen, K. Weeks, G. E. Farrugia, C. Johnson, E. Salimova, D. Donner, H. Kiriazis, H. Kaipananickal, , F. Z. Marques

The paper shows that maternal fibre intake during pregnancy influences offspring cardiovascular health by shaping the gut microbiome and inducing epigenetic changes in the offspring's heart.

bioRxiv · Mar 12, 2022Microbiology

Specific viral RNA drives the SARS CoV-2 nucleocapsid to phase separate

C. Iserman, C. A. Roden, M. Boerneke, R. Sealfon, G. McLaughlin, I. Jungreis, C. Y. Park, A. Boppana, E. Fritch, Y. Hou, C. Theesfeld, O. Troyanskaya, R. S. G. Baric, T. P. Sheahan, K. Weeks, A. Gladfelter

This study shows SARS-CoV-2 N-protein forms liquid-liquid phase separation with specific viral RNA sequences, which is temperature-sensitive and can be modulated by small molecules, offering potential for antiviral drug development.

bioRxiv · Jun 11, 2020 · PreprintBiochemistry

Time-resolved, single-molecule, correlated chemical probing of RNA

J. Ehrhardt, K. Weeks

This study introduces TMO as a chemical probe for time-resolved, single-molecule RNA structure probing, revealing key tertiary interactions in RNase P RNA folding.

bioRxiv · Mar 21, 2020Biochemistry