K. Y. Chen

This study investigates T-cell signaling on soft lipid bilayers, finding early calcium signaling is not mechanosensitive but phosphatase exclusion occurs on soft substrates.

This study identifies CDK13 mutations in melanoma, showing they lead to accumulation of truncated transcripts and poor survival, with a mechanism involving impaired ZC3H14 phosphorylation and PAXT complex recruitment.

This paper describes a method to fabricate zero-mode waveguides (ZMWs) using colloidal lithography, enabling single molecule fluorescence imaging without requiring expensive equipment.

This study compares energy expenditure measurements using doubly labeled water (DLW) and respiratory chambers during very low-carbohydrate diets, finding that DLW overestimates energy expenditure when not adjusted for respiratory quotient changes.

The paper demonstrates stochastic simulation for visualizing gene expression and error correction in cells, using case studies and code samples for educational purposes.