L. Ferretti

Interpreting the pervasive observation of U-shaped Site Frequency Spectra

The paper analyzes site frequency spectra across species and finds U-shaped patterns, suggesting that multiple merger coalescent models better fit the data than the standard neutral model.

The bounded coalescent model: conditioning a genealogy on a minimum root date

The paper introduces a new algorithm for simulating the bounded coalescent model directly, showing improved computational efficiency and providing methods to calculate probabilities under this model.

Cell state diversity promotes metastasis through heterotypic cluster formation in melanoma

This study shows that melanoma metastasis is promoted by heterotypic clusters formed between proliferative and invasive cell states, mediated by TFAP2.

Concordant developmental expression profiles of orthologues in highly divergent Bilateria

The paper identifies conserved genes across Bilateria and shows their expression peaks at the phylotypic stage, supporting the orthologue conjecture.

Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the Foot-and-Mouth Disease Virus capsid

This paper shows that within-host recombination and epistasis significantly drive molecular evolution of FMDV capsid genes, with recombination rates comparable to mutation rates.