Author

L. Dalit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2

Frequent Co-Authors

C. Zaph· 3 shared J. R. Groom· 3 shared L. Hailes· 3 shared A. A. Sheikh· 2 shared A. Zaini· 2 shared C. Alvarado· 2 shared C. W. Tan· 2 shared K. L. Good-Jacobson· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

C. Zaph

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection

B. J. Broomfield, C. W. Tan, R. Z. Qin, B. C. Duckworth, C. Alvarado, L. Dalit, J. Chen, L. Mackiewicz, H. Muramatsu, M. Pellegrini, K. Rogers, W. J. Moon, S. L. Nutt, M. J. Davis, N. Pardi, , J. R. Groom

This paper shows that temporarily blocking type I interferon during viral infection boosts CD8+ T cell memory and vaccine effectiveness by promoting TSCM cell formation.

bioRxiv · Jun 26, 2024Immunology

Divergent cytokine and transcriptional signatures control functional T follicular helper cell heterogeneity

L. Dalit, C. W. Tan, A. A. Sheikh, R. Munnings, C. Alvarado, T. Hussain, A. Zaini, L. Cooper, A. Kirn, L. Hailes, A. Nguyen, L. Mackay, N. Harris, C. Zaph, N. L. La Gruta, , J. R. Groom

The paper identifies transcriptional modules and cytokine signaling pathways that drive functional heterogeneity in T follicular helper cells across different infections.

bioRxiv · Jun 12, 2024Immunology

Heterogeneous Tfh cell populations that develop during enteric helminth infection predict the quality of type 2 protective response

A. Zaini, L. Dalit, A. A. Sheikh, D. Thiele, Y. Zhang, J. Runting, G. Rodrigues, J. Ng, M. Bramhall, S. Scheer, L. Hailes, J. R. Groom, K. L. Good-Jacobson, C. Zaph

This study identifies distinct Tfh cell populations during chronic and acute helminth infections and shows their role in type 2 immune responses.

bioRxiv · Oct 20, 2021Immunology

The histone methyltransferase DOT1L is essential for humoral immune responses

L. Kealy, A. Di Pietro, L. Hailes, S. Scheer, L. Dalit, J. Groom, C. Zaph, K. L. Good-Jacobson

This study shows that DOT1L is essential for B cell development and humoral immune responses, as its deletion leads to impaired germinal center formation and reduced antibody production.

bioRxiv · Jun 19, 2020Immunology