Author

L. Moritz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

S. Hammoud· 2 shared A. Diehl· 1 shared C. Sultan· 1 shared D. L. Caswell· 1 shared D. Pendlebury· 1 shared D. Spevakova· 1 shared F. Liska· 1 shared H. Schorle· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

S. Hammoud

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2 papers

Recent·Most cited

Protamine 2 Deficiency Results In Septin 12 Abnormalities

O. Sanovec, M. Frolikova, V. Kraus, J. Vondrakova, M. Qasemi, D. Spevakova, O. Simonik, L. Moritz, D. L. Caswell, F. Liska, L. Ded, J. Cerny, T. Avidor-Reiss, S. Hammoud, H. Schorle, , K. Komrskova

This study shows that Protamine 2 deficiency leads to Septin 12 abnormalities in sperm, affecting motility and morphology.

bioRxiv · May 28, 2024Cell Biology

Single residue substitution in protamine 1 disrupts sperm genome packaging and embryonic development in mice

L. Moritz, S. Schon, M. Rabbani, Y. Sheng, D. Pendlebury, R. Agrawal, C. Sultan, K. Jorgensen, X. Zheng, A. Diehl, K. Ragunathan, Y.-C. Hu, J. Nandakumar, J. Li, K. Orwig, , S. Hammoud

This study shows that a single amino acid substitution in mouse protamine 1 disrupts DNA packaging and causes infertility by altering protein function and developmental outcomes.

bioRxiv · Sep 16, 2021 · PreprintBiochemistry