PathologybioRxiv
Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice
L. Muniappan, M. Okuyama, A. Javidan…·V. Subramanian
This study shows that calpain-2 depletion reduces abdominal aortic aneurysm (AAA) progression and rupture in mice by preserving cytoskeletal proteins and ECM integrity.
DOI 10.1161/atvbaha.120.315546