Author

V. Subramanian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Bioengineering· 1 Cell Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 5 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Agrawal· 1 shared A. Aron· 1 shared A. Balakrishnan· 1 shared A. Javidan· 1 shared A. Jayaraman· 1 shared A. Kovalenko· 1 shared A. P. Gheware· 1 shared A. Viglione· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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1 shared paperImmunology

A. Agrawal

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Author profile →

6 papers

Recent·Most cited

Visualization of liquid-liquid phase transitions using a tiny G-quadruplex binding protein

B. R. Sahoo, X. Deng, E. L. Wong, N. Clark, H. Yang, V. Subramanian, B. B. Guzman, S. E. Harris, B. Dehury, E. Miyashita, J. D. Hoff, V. Kocman, H. Saito, D. Dominguez, J. Plavec, , A. Kovalenko

The paper identifies SERF2 as a protein involved in stress granule formation and characterizes its interactions with G-quadruplex RNA structures to study liquid-liquid phase transitions.

bioRxiv · Oct 9, 2023Cell Biology

Machine Learning-Guided Antibody Engineering That Leverages Domain Knowledge To Overcome The Small Data Problem

T. Clark, V. Subramanian, A. Jayaraman, E. Fitzpatrick, R. Gopal, N. Pentakota, T. Rurak, S. Anand, A. Viglione, K. Tharakaraman, R. Raman, R. Sasisekharan

This paper presents a machine learning platform that enhances antibody affinity and neutralizing potency using domain knowledge and limited experimental data.

bioRxiv · Jun 2, 2023 · PreprintBioengineering

In Vitro Inactivation of Human Coronavirus by Titania Nanoparticle Coatings and UVC Radiation: Throwing Light on SARS-CoV-2

S. Khaiboullina, T. Uppal, N. Dhabarde, V. Subramanian, S. C. Verma

This study investigates the virucidal efficacy of titania nanoparticles under UV radiation against HCoV-NL63, a close relative of SARS-CoV-2, using RT-PCR and virus culture assays.

bioRxiv · Aug 25, 2020Microbiology

Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut.

H. Zhi, J. Behnsen, A. Aron, V. Subramanian, J. Liu, R. Gerner, D. Petras, K. Green, S. Price, J. Camacho, H. Hillman, J. Tjokrosurjo, N. Montaldo, E. Hoover, S. Treacy-Abarca, , M. Raffatellu

This study shows that the probiotic E. coli Nissle 1917 uses yersiniabactin to acquire zinc in inflamed gut conditions, enhancing its colonization.

bioRxiv · Jul 20, 2020Microbiology

Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice

L. Muniappan, M. Okuyama, A. Javidan, D. Thiagarajan, W. Jiang, J. J. Moorleghen, L. Yang, A. Balakrishnan, D. Howatt, H. A. Uchida, T. C. Saido, V. Subramanian

This study shows that calpain-2 depletion reduces abdominal aortic aneurysm (AAA) progression and rupture in mice by preserving cytoskeletal proteins and ECM integrity.

bioRxiv · Apr 15, 2020Pathology

Adhatoda Vasica ameliorates cellular hypoxia dependent mitochondrial dysfunction in acute and severe asthmatic mice.

A. P. Gheware, L. Panda, K. Khanna, N. K. Bhatraju, V. Jain, S. Sagar, M. Kumar, V. P. Singh, S. Kannan, V. Subramanian, M. Mukerji, A. Agrawal, B. Prasher

This study shows Adhatoda Vasica extract reduces hypoxia-induced mitochondrial dysfunction and inflammation in asthma models, offering potential for treating severe steroid-resistant asthma.

bioRxiv · Apr 1, 2020 · PreprintImmunology