Author

L. Regad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Haouz· 1 shared A. Mechaly· 1 shared A. Wilson· 1 shared E. Rojas· 1 shared F. Rodrigues-Lima· 1 shared F. Samaniego· 1 shared H. Yang· 1 shared J. Henderson· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Haouz

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1 paper

Recent·Most cited

CREBBP lysine acetyltransferase domain mutations create zombie enzymes that alter chromatin loading dynamics and prevent EP300 redundancy

H. Yang, W. Zhang, V. Ravanmehr, A. Mechaly, L. Regad, A. Haouz, R. Chen, J. Henderson, E. Rojas, A. Wilson, S. Parsons, L. Nastoupil, R. E. Davis, Q. Deng, F. Samaniego, , M. R. Green

The paper shows that CREBBP mutations disrupt chromatin loading dynamics and EP300 redundancy, creating zombie enzymes that impair enhancer activation in GC B-cells and lymphoma.

bioRxiv · Sep 5, 2023 · PreprintCancer Biology