Cell BiologybioRxiv
Syntenin and CD63 Promote Exosome Biogenesis from the Plasma Membrane by Blocking Cargo Endocytosis
Y. Ai, C. Guo, M. Garcia-Contreras…·S. Gould
This study shows that syntenin and CD63 promote exosome biogenesis by blocking CD63 endocytosis, allowing it to accumulate at the plasma membrane where exosomes originate.
DOI 10.1126/sciadv.adi9156