Author

M. Garcia-Contreras

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:non-human primate· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

A. C. Yang· 1 shared A. Saftics· 1 shared B. Carlson· 1 shared B. Smith· 1 shared C. Guo· 1 shared C. P. Lai· 1 shared C. R. Bertozzi· 1 shared E. K. Hutchinson· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperBiochemistry

A. C. Yang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Syntenin and CD63 Promote Exosome Biogenesis from the Plasma Membrane by Blocking Cargo Endocytosis

Y. Ai, C. Guo, M. Garcia-Contreras, L. S. Sanchez, A. Saftics, O. Shodubi, S. Raghunandan, J. Xu, S.-J. Tsai, Y. Dong, R. Li, T. Jovanovic-Talisman, S. Gould

This study shows that syntenin and CD63 promote exosome biogenesis by blocking CD63 endocytosis, allowing it to accumulate at the plasma membrane where exosomes originate.

bioRxiv · May 26, 2023Cell Biology

Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina

T. Driedonks, L. Jiang, B. Carlson, Z. Han, G. Liu, S. E. Queen, E. N. Shirk, O. Gololobova, L. H. Nyberg, G. Lima, L. Paniushkina, M. Garcia-Contreras, K. Schonvisky, M. Stover, S. Guerrero-Martin, , K. W. Witwer

This study investigates the pharmacokinetics and biodistribution of extracellular vesicles in macaques via intravenous and intranasal routes, finding longer plasma circulation times and organ uptake with IV administration, but limited systemic distribution with IN.

bioRxiv · Jul 28, 2021Pharmacology & Toxicology

Cell type-selective secretome profiling in vivo

W. Wei, N. M. Riley, A. C. Yang, J. T. Kim, S. M. Terrell, V. L. Li, M. Garcia-Contreras, C. R. Bertozzi, J. Z. Long

The paper introduces a method to profile cell-type-specific secretomes in vivo and identifies novel secreted proteins and dynamic changes in hepatocyte secretomes.

bioRxiv · Sep 18, 2020Biochemistry