Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway
J. Zhang, J. Chang, V. Chen, M. A. Beg, W. Huang, L. Vick, Y. Wang, H. Zhang, E. Yttre, A. Gupta, M. Castleberry, Z. Zhang, W. Dai, S. Song, J. Zhu, , Y. Chen
This study identifies the CD36-PKM2-mtROS pathway as a mechanism by which oxidized LDL disrupts efferocytosis, contributing to atherosclerosis progression.
bioRxiv · Sep 7, 2023 · PreprintImmunology