Author

M. A. Blanco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

N. Li· 2 shared X. Wang· 2 shared Y. Tian· 2 shared Z. Cramer· 2 shared B. W. Katona· 1 shared C. J. Lengner· 1 shared C. Lengner· 1 shared D. Mendez· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

N. Li

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Forward genetic screening in engineered colorectal cancer organoids identifies novel regulators of metastasis

Z. Cramer, X. Wang, N. A. Leu, K. Monaghan, J. H. Rhoades, Y. Tian, J. Rico, D. Mendez, R. Petroni, M. S. Kim, R. Matsuda, M. F. Carrera, I. E. Brodsky, N. Li, C. J. Lengner, M. A. Blanco

The paper uses CRISPR/Cas9 screening in colorectal cancer organoids to identify novel metastasis regulators, finding Ctnna1 and Bcl2l13 as metastasis suppressors.

bioRxiv · Aug 3, 2023 · PreprintCancer Biology

APC and P53 mutations synergize to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer

Y. Tian, X. Wang, Z. Cramer, J. Rhoades, K. N. Estep, X. Ma, S. A. Tzivelekidis, B. W. Katona, F. B. Johnson, Z. Yu, M. A. Blanco, C. Lengner, N. Li

This study identifies NOTUM as a therapeutic target in advanced colorectal cancer, showing that its inhibition effectively arrests tumor growth and metastasis in models with APC and P53 mutations.

bioRxiv · Jul 26, 2022 · PreprintCancer Biology