Author

J. Rhoades

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

B. W. Katona· 1 shared C. Lengner· 1 shared D. Shea· 1 shared E. Nguyen· 1 shared F. B. Johnson· 1 shared G. Gydush· 1 shared G. M. Makrigiorgos· 1 shared J. H. Bae· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

B. W. Katona

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Author profile →

2 papers

Recent·Most cited

APC and P53 mutations synergize to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer

Y. Tian, X. Wang, Z. Cramer, J. Rhoades, K. N. Estep, X. Ma, S. A. Tzivelekidis, B. W. Katona, F. B. Johnson, Z. Yu, M. A. Blanco, C. Lengner, N. Li

This study identifies NOTUM as a therapeutic target in advanced colorectal cancer, showing that its inhibition effectively arrests tumor growth and metastasis in models with APC and P53 mutations.

bioRxiv · Jul 26, 2022 · PreprintCancer Biology

CODEC enables 'single duplex' sequencing

J. H. Bae, R. Liu, E. Nguyen, J. Rhoades, T. Blewett, K. Xiong, D. Shea, G. Gydush, S. Tabrizi, Z. An, S. Patel, G. M. Makrigiorgos, T. R. Golub, V. A. Adalsteinsson

CODEC improves mutation detection by combining NGS throughput with single-molecule resolution, achieving similar accuracy with fewer reads.

bioRxiv · Jun 11, 2021Bioengineering