Cancer BiologybioRxiv
BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma
Y. Feng, L. Cai, M. Pook…·S. Pauklin
This study identifies BRD9 as a key regulator of pancreatic cancer stem cell stemness and tumorigenesis, showing that its inhibition reduces CSC self-renewal and enhances chemotherapy response.
DOI 10.1053/j.gastro.2023.09.021