M. Arroyo

Mapping mechanical stress in curved epithelia of designed size and shape

The paper maps mechanical stress in engineered curved epithelial monolayers of controlled size and shape, showing size-independent stress increases and stress anisotropies in rectangular and ellipsoidal geometries.

Patterning of membrane adhesion under hydraulic stress

The paper studies hydraulic fracturing in cell membranes under osmotic stress to understand microlumen formation and dynamics.

The laminin-keratin link shields the nucleus from mechanical deformation and signalling

This study shows laminin-111 shields the nucleus from mechanical deformation by linking integrin {beta}4 to keratin, affecting YAP localization and chromatin methylation in breast epithelial cells.

A mechanosensing mechanism mediated by IRSp53 controls plasma membrane shape homeostasis at the nanoscale

The paper identifies a mechanosensing mechanism involving IRSp53 that detects and restores plasma membrane nano-scale deformations through actin polymerization.

Dynamic Mechanochemical feedback between curvedmembranes and BAR protein self-organization

This study investigates how BAR proteins dynamically interact with curved membranes and how their organization depends on membrane shape and mechanical stimuli.

Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration

This study maps mechanical forces in mouse intestinal organoids, revealing how stress patterns drive crypt folding and cell migration through compartmentalization.

A physical mechanism of TANGO1-mediated bulky cargo export

This paper presents a physical model explaining how TANGO1 stabilizes ER membrane tension to facilitate procollagen export from the ER.