Author

M. D. Scharff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Y. Zhang· 2 shared C. Tangcatherin· 1 shared E. Tosti· 1 shared G. Yu· 1 shared J. Aguilan· 1 shared J. van Oers· 1 shared K. Lee· 1 shared P. Cohen· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

Y. Zhang

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2 papers

Recent·Most cited

Locus-specific proteomics identifies new aspects of the chromatin context involved in V region somatic hypermutation

G. Yu, Z. Duan, Y. Zhang, J. Aguilan, S. Sidoli, M. D. Scharff

The paper uses locus-specific proteomics to identify proteins associated with the V region chromatin in SHM and validates their function using a Dot1L inhibitor.

bioRxiv · Sep 8, 2022 · PreprintImmunology

Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1D173A mice

S. Wang, K. Lee, S. Gray, Y. Zhang, C. Tangcatherin, R. Morrish, E. Tosti, J. van Oers, P. Cohen, T. MacCarthy, S. Roa, M. D. Scharff, W. Edelmann, R. Chahwan

This study compares Exo1DA/DA mice with nuclease-dead EXO1 to Exo1-/- and Exo1+/+ mice to show EXO1 has both enzymatic and scaffolding roles in DNA repair, immune response, and tumor suppression.

bioRxiv · Oct 5, 2021Cancer Biology