Author

M. De Santis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

D. Dubnau· 2 shared J. Hahn· 2 shared A. Broggi· 1 shared A. Lo Cascio· 1 shared B. Sposito· 1 shared C. Aumeier· 1 shared C. Leterrier· 1 shared D. Inoue· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersMicrobiology

D. Dubnau

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mechanisms of transforming DNA uptake to the periplasm of Bacillus subtilis

J. Hahn, M. De Santis, D. Dubnau

This study shows that DNA uptake in Bacillus subtilis occurs in the periplasm, not the cytoplasm, and identifies the roles of ComEA, ComEC, and NucA in this process.

bioRxiv · Mar 9, 2021Microbiology

ComEB protein is dispensable for transformation but must be translated for optimal synthesis of ComEC

M. De Santis, J. Hahn, D. Dubnau

The paper shows ComEB is not required for transformation in Bacillus subtilis but is needed for optimal ComEC synthesis through translational coupling.

bioRxiv · Dec 30, 2020Microbiology

Type III interferons disrupt the lung epithelial barrier upon viral recognition.

A. Broggi, S. Ghosh, B. Sposito, R. Spreafico, F. Balzarini, A. Lo Cascio, N. Clementi, M. De Santis, N. Mancini, F. Granucci, I. Zanoni

This study shows that type III interferons from lung dendritic cells damage the epithelial barrier and increase susceptibility to bacterial infections during viral recognition.

bioRxiv · May 5, 2020Immunology

Self-repair protects microtubules from their destruction by molecular motors

S. Triclin, D. Inoue, J. Gaillard, Z. M. Htet, M. De Santis, D. Portran, E. Derivery, C. Aumeier, L. Schaedel, K. John, C. Leterrier, S. Reck-Peterson, L. Blanchoin, M. Thery

The paper investigates how molecular motors affect microtubule stability and discovers a self-repair mechanism that counteracts motor-induced damage.

bioRxiv · Dec 17, 2018Cell Biology