Author

M. Distel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:zebrafish· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

F. Halbritter· 3 shared A. Wenninger-Weinzierl· 2 shared C. Sturtzel· 2 shared E. Bozsaky· 2 shared L. E. Shaw· 2 shared M. Farlik· 2 shared M. R. Shoeb· 2 shared R. Ladenstein· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

F. Halbritter

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cross-species analysis identifies conserved transcriptional mechanisms of neutrophil maturation

S. Kirchberger, M. R. Shoeb, D. Lazic, K. Fischer, L. E. Shaw, F. Nogueira, F. Rifatbegovic, E. Bozsaky, R. Ladenstein, B. Bodenmiller, T. Lion, D. Traver, M. Farlik, S. Taschner-Mandl, F. Halbritter, M. Distel

The paper identifies conserved transcriptional mechanisms of neutrophil maturation across zebrafish, mouse, and human by generating high-resolution transcriptional profiles and cross-species comparisons.

bioRxiv · Nov 28, 2022Immunology

A human neural crest model reveals the developmental impact of neuroblastoma-associated chromosomal aberrations

I. M. Saldana-Guerrero, L. F. Montano-Gutierrez, K. Boswell, C. Hafemeister, E. Poon, L. E. Shaw, D. Stavish, R. A. Lea, S. Wernig-Zorc, E. Bozsaky, I. S. Fetahu, P. Zoescher, U. Pötschger, M. Bernkopf, A. Wenninger-Weinzierl, , F. Halbritter

The paper uses human embryonic stem cells to show that chromosomal gains in neuroblastoma impair neural crest development and enhance MYCN-driven tumourigenesis.

bioRxiv · Nov 21, 2022Cancer Biology

ROS induction as a strategy to target persister cancer cells with low metabolic activity in NRAS mutated melanoma

O. M. Eichhoff, C. I. Stoffel, J. Kaesler, L. Briker, P. Turko, G. Karsai, N. Zila, V. Paulitschke, P. F. Cheng, A. Leitner, A. Bileck, N. Zamboni, A. Irmisch, Z. Balazs, A. Tastanova, , M. Levesque

The paper identifies ROS induction as a strategy to target MEK-inhibitor resistant NRAS-mutated melanoma cells by exploiting their quiescent metabolic state and elevated baseline ROS levels.

bioRxiv · Oct 19, 2022 · PreprintCancer Biology

Automated compound testing in zebrafish xenografts identifies combined MCL-1 and BCL-XL inhibition to be effective against Ewing sarcoma

S. Grissenberger, C. Sturtzel, A. Wenninger-Weinzierl, E. Scheuringer, L. Bierbaumer, S. Pascoal, M. Toetzl, E. Tomazou, O. Delattre, D. Surdez, H. Kovar, F. Halbritter, M. Distel

bioRxiv · Jun 17, 2021 · PreprintCancer Biology

In vivo photocontrol of microtubule dynamics and integrity, migration and mitosis, by the potent GFP-imaging-compatible photoswitchable reagents SBTubA4P and SBTub2M

L. Gao, J. C. M. Meiring, A. Varady, I. E. Ruider, C. Heise, M. Wranik, C. D. Velasco, J. A. Taylor, B. Terni, J. Standfuss, C. C. Cabernard, A. Llobet, M. O. Steinmetz, A. R. Bausch, M. Distel, , O. Thorn-Seshold

This paper introduces two new photoswitchable reagents for in vivo control of microtubule dynamics and related processes, showing their effectiveness in 3D systems and model organisms.

bioRxiv · Mar 26, 2021Cell Biology