Author

A. Thapa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Cancer Biology· 1 Ecology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

R. D. Mohan· 2 shared V. Cloud· 2 shared A. Bharadwaj· 1 shared A. Bhat· 1 shared A. Biswakarma· 1 shared A. Blake· 1 shared A. Burns· 1 shared A. G. Abraham· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

R. D. Mohan

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Understanding inter-individual social networks in mixed-species bird flocks

A. Bharadwaj, A. Thapa, A. Bhat, A. Biswakarma, B. Tamang, B. Munda, B. Biswakarma, D. K. Pradhan, D. Tamang, K. Pradhan, M. K Rai, P. Chamling Rai, R. Rai, S. Rai, U. Srinivasan

This study constructs individual-level social networks in mixed-species bird flocks in the Eastern Himalaya, revealing differences in flock structure and mechanisms between two flocktypes.

bioRxiv · Apr 13, 2023Ecology

Constitutively synergistic multiagent drug formulations targeting MERTK, FLT3, and BCL-2 for treatment of AML

J. M. Kelvin, J. Jain, A. Thapa, M. Qui, L. A. Birnbaum, S. G. Moore, H. Zecca, R. J. Summers, E. Costanza, B. Uricoli, X. Wang, N. T. Jui, H. Fu, Y. Du, D. DeRyckere, , E. C. Dreaden

The paper develops a nanoscale combination drug formulation targeting MERTK, FLT3, and BCL-2 to treat AML, showing improved synergistic responses in vitro and in patient samples.

bioRxiv · Mar 13, 2023 · PreprintBioengineering

Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling

H. A. Danhof, J. Lee, A. Thapa, R. A. Britton, S. C. Di Rienzi

This study identifies oxytocin as an intestinal hormone produced and secreted by enterocytes in response to secretin stimulation by L. reuteri.

bioRxiv · Mar 9, 2023Microbiology

TET2 drives 5hmc marking of GATA6 and epigenetically defines pancreatic ductal adenocarcinoma transcriptional subtypes

M. Eyres, S. Lanfredini, A. Burns, A. Blake, F. Willenbrock, R. Goldin, D. Hughes, S. Hughes, A. Thapa, D. Valoulis, A. Hubert, Z. D'Costa, A. Sabbagh, A. G. Abraham, C. Blancher, , E. O'Neill

This study identifies TET2-driven 5hmc loss at GATA6 as a mechanism defining PDAC transcriptional subtypes and shows that TET2 stabilization with Metformin and Vitamin C reverses squamous-like tumor features.

bioRxiv · Oct 22, 2020Cancer Biology

Ataxin-7 and non-stop coordinate SCAR protein levels, subcellular localization, and actin cytoskeleton organization

V. Cloud, A. Thapa, P. Morales-Sosa, T. Miller, E. Momtahan, J. L. Jack, P. Gerhart, E. Leiva, S. R. Rapp, S. A. Miller, D. Holsapple, L. G. Shelton, R. A. Pierce, S. Martin-Brown, L. Florens, , R. D. Mohan

bioRxiv · Jun 25, 2019Cell Biology

Brief Freezing Steps Lead to Robust Immunofluorescence in Drosophila Larval Brains

D. Buckley, A. Thapa, M. Nguyen, E. Blankinship, D. Williamson, V. Cloud, R. D. Mohan

The paper compares immunofluorescence techniques for Drosophila larval brains, finding that freezing improves staining without compromising structural integrity.

bioRxiv · May 13, 2018Cell Biology