Author

M. Giannotta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:imaging· 4 Research Focus:drug response / drug discovery· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:clustering· 2 Organism:human· 2

Frequent Co-Authors

C. Maderna· 3 shared F. Iannelli· 3 shared N. Kakogiannos· 3 shared E. Dejana· 2 shared G. Pelicci· 2 shared H. Fan· 2 shared M. Crestani· 2 shared P. Maiuri· 2 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiophysics

C. Maderna

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Unraveling Glioblastoma Heterogeneity: Introducing SP2G Method for Identifying Invasive Sub-Populations

M. Crestani, N. Kakogiannos, F. Iannelli, T. Dini, C. Maderna, M. Giannotta, G. Pelicci, P. Maiuri, P. Monzo, N. Gauthier

The paper introduces SP2G, a method to identify invasive sub-populations in glioblastoma cells by analyzing their motility on gridded micropatterns and linking it to molecular markers.

bioRxiv · Jan 10, 2024 · PreprintBiophysics

SP2G: an imaging and analysis pipeline revealing the inter and intra-patient migratory diversity of glioblastoma

M. Crestani, N. Kakogiannos, F. Iannelli, T. Dini, C. Maderna, M. Giannotta, G. Pelicci, P. Maiuri, P. Monzo, N. C. Gauthier

SP2G identifies invasive glioblastoma sub-populations through an in vivo mimicry platform and imaging analysis, revealing intra-patient heterogeneity in cell motility.

bioRxiv · Feb 24, 2023 · PreprintBiophysics

Dual role of brain endothelial Gpr126 in blood-brain barrier development and ischemic stroke

N. Kakogiannos, A. A. Scalise, E. Martini, C. Maderna, S. Magni, G. S. Gullotta, M. G. Lampugnani, F. Iannelli, G. Beznusenko, A. Mironov, C. Cerutti, K. Bentley, A. Philippides, F. Zanardi, M. Bacigaluppi, , M. Giannotta

This study identifies Gpr126 as a regulator of BBB development and shows its detrimental role in ischemic stroke, with potential therapeutic implications.

bioRxiv · Sep 9, 2022 · PreprintCell Biology

Optical Modulation of Blood-Brain-Tumor Barrier Permeability Enhances Drug Delivery in Diverse Preclinical Glioblastoma Models

Q. Cai, X. Li, H. Xiong, H. Fan, X. Gao, V. Vemireddy, R. Margolis, J. Li, X. Ge, M. Giannotta, E. Dejana, K. Hoyt, R. Bachoo, Z. Qin

This study demonstrates that optical modulation of the blood-brain-tumor barrier enhances drug delivery and suppresses tumor growth in glioblastoma models.

bioRxiv · Jun 7, 2022 · PreprintBioengineering

Calcium-Mediated Modulation of Blood-Brain Barrier Permeability by Laser Stimulation of Endothelial-Targeted Nanoparticles

X. Li, Q. Cai, B. A. Wilson, H. Fan, M. Giannotta, R. Bachoo, Z. Qin

This study investigates how laser stimulation of endothelial-targeted nanoparticles increases blood-brain barrier permeability through calcium signaling and cytoskeletal changes.

bioRxiv · Jun 2, 2022 · PreprintBioengineering