N. Gauthier

Unraveling Glioblastoma Heterogeneity: Introducing SP2G Method for Identifying Invasive Sub-Populations

The paper introduces SP2G, a method to identify invasive sub-populations in glioblastoma cells by analyzing their motility on gridded micropatterns and linking it to molecular markers.

Mechanically induced topological transition of spectrin regulates its distribution in the mammalian cortex

This study shows spectrin in mammalian cells can transition between different topological structures under mechanical stress, adapting to protect the cell cortex.

PIP4K2B is a mechanosensor and induces heterochromatin-driven nuclear softening through UHRF1.

The paper identifies PIP4K2B as a mechanosensor that induces nuclear softening via UHRF1, affecting YAP activity and cell motility in cancer.

Theoretical model of efficient phagocytosis driven by curved membrane proteins and active cytoskeleton forces

This paper presents a theoretical model explaining how curved membrane proteins and active cytoskeletal forces drive efficient phagocytosis, showing reduced adhesion strength requirements and faster engulfment.

Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike

This study evaluates humoral responses against SARS-CoV-2 Spike in 106 infected individuals, finding persistent RBD-specific IgG and declining neutralizing activity over time.

Mesoscale Dynamics of Spectrin and Acto-Myosin shape Membrane Territories during Mechanoresponse

The paper investigates how spectrin and acto-myosin cytoskeletons dynamically reorganize during mechanical challenges to support membrane territories.

Membrane-cytoskeleton mechanical feedback mediated by myosin-I controls phagocytic efficiency

The paper shows that myosin 1e and 1f are required for efficient phagocytosis by regulating adhesion turnover and actin dynamics during phagocytic cup closure.