Author

K. Bentley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Research Focus:development & morphogenesis· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Woodman· 2 shared F. G. Alnaji· 2 shared A. A. Scalise· 1 shared A. Buckley· 1 shared A. Macadam· 1 shared A. Mironov· 1 shared A. Pearson· 1 shared A. Philippides· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

A. Woodman

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Hybrid immunity elicits potent cross-variant ADCC against SARS-CoV-2 through a combination of anti-S1 and S2 antibodies

M. D. Grant, K. Bentley, C. A. Fielding, K. M. Hatfield, D. P. Ings, D. Harnum, E. Wang, R. Stanton, K. A. Holder

This study shows that hybrid immunity, from prior infection followed by vaccination, generates stronger and broader antibody-dependent cellular cytotoxicity (ADCC) against SARS-CoV-2 variants than vaccination alone.

bioRxiv · Mar 9, 2023 · PreprintImmunology

Dual role of brain endothelial Gpr126 in blood-brain barrier development and ischemic stroke

N. Kakogiannos, A. A. Scalise, E. Martini, C. Maderna, S. Magni, G. S. Gullotta, M. G. Lampugnani, F. Iannelli, G. Beznusenko, A. Mironov, C. Cerutti, K. Bentley, A. Philippides, F. Zanardi, M. Bacigaluppi, , M. Giannotta

This study identifies Gpr126 as a regulator of BBB development and shows its detrimental role in ischemic stroke, with potential therapeutic implications.

bioRxiv · Sep 9, 2022 · PreprintCell Biology

Imprecise recombinant viruses evolve via a fitness-driven, iterative process of polymerase template-switching events.

K. Bentley, F. G. Alnaji, L. Woodford, S. Jones, A. Woodman, D. J. Evans

The paper investigates how imprecise recombinant viruses evolve through fitness-driven recombination and resolution processes, showing that resolution involves repeated recombination events leading to wild-type genomes.

PLOS Pathogens · Aug 20, 2021Peer-reviewedMicrobiology

Pilot study: Trehalose-induced remodelling of the human microbiota affects Clostridioides difficile infection outcome in an in vitro colonic model

A. Buckley, I. Moura, N. Arai, W. Spittal, E. Clark, Y. Nishida, H. Harris, K. Bentley, G. DAVIS, D. Wang, S. Mitra, T. Higashiyama, M. H. Wilcox

This study shows that trehalose supplementation remodels the human gut microbiota, preventing simulated Clostridioides difficile infection in an in vitro model.

bioRxiv · Feb 16, 2021Microbiology

Generated randomly and selected functionally? The nature of enterovirus recombination

F. G. Alnaji, K. Bentley, A. Pearson, A. Woodman, J. D. Moore, H. Fox, A. Macadam, D. Evans

This study investigates the factors influencing recombination in poliovirus, finding that genome function and fitness, rather than sequence identity or structure, determine the identity of recombinant progeny.

bioRxiv · Sep 29, 2020Microbiology

Active Perception during Angiogenesis: Filopodia speed up Notch selection of tip cells in silico and in vivo

B. Zakirov, G. Charalambous, I. M. Aspalter, K. Van-Vuuren, T. Mead, K. Harrington, R. Thuret, E. Ravasz Regan, S. P. Herbert, K. Bentley

This study shows filopodia enhance Notch-mediated tip cell selection during angiogenesis through active perception mechanisms in both simulations and zebrafish embryos.

bioRxiv · Aug 22, 2020Cell Biology