Author

M. Grade

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

G. Emons· 2 shared J. Camps· 2 shared J. Gaedcke· 2 shared t. ried· 2 shared Y. Hu· 2 shared A. Lischka· 1 shared B. M. Ghadimi· 1 shared B. Ross· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

G. Emons

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3 papers

Recent·Most cited

Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair

M. Silva-Garcia, O. Bolgi, B. Ross, E. Pilla, K. Vijayalakshmi, M. Killisch, N. Stark, C. Lenz, M. Spitzner, M. D. Gorrell, M. Grade, H. Urlaub, M. Dobbelstein, R. Huber, R. Geiss-Friedlander

This study identifies DPP9 as a regulator of BRCA2 stability and DNA-damage repair by promoting its degradation via the N-degron pathway.

bioRxiv · Aug 24, 2020Biochemistry

Cancer-type specific aneuploidies hard-wire chromosome-wide gene expression patterns of their tissue of origin

N. Auslander, K. Heselmeyer-Haddad, S. Patkar, D. Hirsch, J. Camps, M. Brown, D. Bronder, W.-D. Chen, R. Lokanga, D. Wangsa, D. Wangsa, Y. Hu, A. Lischka, R. Braun, G. Emons, , t. ried

The paper shows cancer-type specific aneuploidies correlate with normal tissue gene expression patterns, suggesting they hard-wire chromosome-wide expression levels to support tumorigenesis.

bioRxiv · Mar 1, 2019Cancer Biology

Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery

Y. Hu, J. Gaedcke, G. Emons, T. Beissbarth, M. Grade, P. Jo, M. Yeager, S. Chanock, H. Wolff, J. Camps, M. B. Ghadimi, T. Ried

This study identifies three colorectal cancer risk loci associated with poor prognosis in rectal cancer patients and links some SNPs to chemoradiotherapy resistance.

bioRxiv · Jun 30, 2017Cancer Biology