M. H. Oktay

This study identifies a mechanism by which macrophages induce MenaINV expression in breast cancer cells through cooperative NF-κB and Notch1 signaling, leading to increased metastasis.

The paper uses intravital imaging to show macrophage-induced cancer stem cells (CSCs) are enriched at TMEM doorways during metastasis, with CSCs comprising >60% of circulating tumor cells.